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New Sanger alleles available

(25-Jan-2017, updated 21-Feb-2017)

Nearly 6,000 new Sanger alleles are now available, with several thousands more to follow in the course of 2017.

Show new alleles...

 

Archiving of zebrafish lines can reduce animal experiments in biomedical research

(23-Dec-2016)

Opinion article in EMBO Reports.

Read here...

 

ZFIN funding major concern

(24-Jun-2016)

Our collaborators at the ZFIN model organism database need your help.

Read and sign the Statement of Support here...

 

EZRC wish list

(22-Dec-2015)

The EZRC aims to increase its exchange of lines with the Zebrafish International Resource Center (ZIRC) in Eugene, Oregon, in order to provide access to these lines to European users without transatlantic shipping charges.
 
Therefore we ask you to kindly send us your wish list of mutant, transgenic, or wild type lines from ZIRC that you would like to see included in our future catalog.

Once a sufficient number of suggestions have been received we will import the requested lines from ZIRC. You will then be able to order them as embryos at our regular prices, to be shipped one generation (aprox. 6 months) later. If you are in a hurry, you will be welcome to visit us to pick up the adult fish at our facility.

Placing lines on the wish list does not oblige you in any way to buy the lines from us later. However, we reserve the right to rank your suggestions based on urgency and expected community interest and if necessary, we will limit the number of lines suggested by a particular lab. For that reason please provide a short explanation why you would like us to import a particular line. Of course we will keep this information confidential.

You may also suggest lines from sources other than ZIRC. However, we may not be able to obtain such lines because of availability and licensing issues.

Please submit your wish list here: http://ezrc.kit.edu/wish_list.php

 

Christmas break

(17-Dec-2015)

The EZRC is closed for the Christmas break from Monday 21th December until Monday 11th January. We wish you a merry Christmas and a happy New Year!

 

Practical introduction to sperm freezing and IVF methods available

(4-Nov-2015, updated 20-Jul-2016)

Get an individual, hands-on introduction to sperm freezing and IVF methods at our lab.

The introduction will take one day, from 9 AM to 3 PM. It is available in English, German or French.

Fee: 600 € for 1 - 2 participants

Please inquire at: ezrc-requests∂itg.kit.edu

 

ZF-HEALTH Symposium 2015, June 4, Gif-sur-Yvette, France

(20-May-2015)

Dear colleagues,

We are pleased to invite you to attend the ZF-HEALTH Symposium 2015 “The Zebrafish: A Vertebrate Model Organism for Biological and Biomedical Investigations” that follows the training course “ZF-Health Resources for in Silico Experimentation”.

The one day conference will take place in Gif-sur-Yvette, France, June 4, 2015. 

Speakers:

 

  • Francesco Argenton (Univ. Padova)
  • Michael Richardson (Univ. Leiden)
  • Olaf Ronneberger (Univ. Freiburg)
  • Wolfgang Driever (Univ. Freiburg)
  • Owen Randlett (Cambridge USA)
  • Claire Wyart (ICM Paris)
  • Nicolas David (ENS Paris)
  • Nadine Peyriéras (CNRS Gif-sur-Yvette)

 

For further information please download the ZF-HEALTH Symposium Flyer (PDF).

The meeting is free of charge for registered participants. Please register here: http://www.ezrc.kit.edu/zf_health_symposium_2015.php

Registration deadline: June 3, 2015

We kindly ask you to forward the announcement to your colleagues as well.

Information on the training course (June 1-3, 2015) is also available at

http://zf-health.org/information/courses.html .

We hope to welcome you and your colleagues in Gif-sur-Yvette.

Kind regards,

Organizing secretary

Jana Maier
Karlsruhe Institute of Technology (KIT)
Hermann-von-Helmholtz-Platz 1
D-76344 Eggenstein-Leopoldshafen
Germany
Telephone: +49-721-608-22716
Fax: +49-721-608-23354
E-mail: jana.maier∂kit.edu

 

ZF-HEALTH workshop: ZF-HEALTH resources for in silico experimentation - VIBE-Z – BioEmergences – MecaGen 

(13-May-2015)

The EU FP7 Integrated Project ZF-HEALTH invites you to attend a training course for using its computation tools and resources (June 1-3, 2015, Gif-sur-Yvette, France).

Read more..

 

European Zebrafish Meeting 2015

(15-Apr-2015)

We will have a booth at the European Zebrafish Meeting in Oslo (June 28 – July 2, 2015), and will be ready to answer your questions. See you in Norway!

Learn more about EZM 2015...

 

International Zebrafish and Medaka Courses (IZMC) held regularly

(22-Mar-2015, updated 4-Nov-2015)

Following the success of our first course, International Zebrafish and Medaka Courses are now held several times a year. They are open to graduates, postgraduates and PIs and follow the FELASA B concept.

Register here for the next available course...

 

PhD positions available

(15-Mar-2015)

PhD positions in bioinformatics ("Rapid identification of ENU mutants by HTS sequencing") and molecular biology ("RNA editing in skeletal muscle during development") are currently open as part of the ZENCODE-ITN training network.

Read more...

 

International Zebrafish and Medaka Course (IZMC)

(5-Jun-2014)

 

Register now for our first International Zebrafish and Medaka Course, July 14 - 18, 2014. It is open to technicians, students, graduates, postgraduates and PIs and will follow the FELASA B concept.

Read more...

 

Open technician position

(3-Apr-2014)

We have an opening for a technician.

Read job posting (in German)...

 

Open PhD position

(15-Nov-2013)

The Institute of Genetics and Toxicology and the European Zebrafish Resource Center at the Karlsruhe Institute of Technology are looking for an outstanding candidate who will develop a PhD research programme in a transdisciplinary team of biologists, engineers and informaticians. The candidate should have an excellent background in molecular cell biology, developmental genetics and have a flair for engineering and computing.

As part of a genome-wide collaborative screen of zebrafish knock-out mutations provided by the Sanger Institute we want to characterize the genes necessary for the earliest behavior of the zebrafish, namely the light-induced motility before hatching and in larval stages up to day 5. We will use a highly automated photomotor response (PMR) assay that is based on the one  developed by the laboratory of Randall Peterson (Harvard University) and which we have established at the KIT in collaboration with him. In chemical screens, this assay has allowed to functionally characterize known psychoactive substances and to identify new candidate molecules. In our genetic screen, we will identify genes affecting the photomotor response and compare these responses to those previously observed for particular psychotropic drugs. The candidate shall participate in the screens and develop a PhD programme within this research framework.

The candidate will participate in the BioInterfaces International Graduate School that offers a structured PhD programme with specialized training opportunities including soft skill courses, seminars and summer schools in a highly interdisciplinary environment.

For further information see

http://www.itg.kit.edu/
http://www.ezrc.kit.edu/
https://www.bif-igs.kit.edu/

or contact Dr. Robert Geisler
robert.geisler∂kit.edu

or Prof. Dr. Uwe Strähle
uwe.straehle∂kit.edu

 

EZRC website online

(8-Nov-2013)

Our new website with a searchable catalog of fish lines is now publicly accessible at http://ezrc.kit.edu

 

Tübingen mutants now available

(27-Sep-2013)

Almost all of the published mutants from the three large-scale Tübingen screens are now available from the EZRC, as embryos from the original frozen sperm samples which were transferred to the EZRC:

Tübingen I: Over 1,000 lines from the ENU mutagenesis screen conducted in 1993 - 1996 by the laboratory of Christiane Nüsslein-Volhard at the Max Planck Institute for Developmental Biology. Some of the published lines have not yet been sequenced ("unm..." genotypes).

Tübingen 2000: ENU mutagenesis screen conducted in 1999 - 2002 by the laboratory of Christiane Nüsslein-Volhard and Artemis Pharmaceuticals GmbH. Only a small number of lines have been published.

Tübingen EU: Over 1,000 lines from the ENU mutagenesis screen conducted in 2004 - 2008 by the ZF-MODELS EU consortium in the laboratory of Christiane Nüsslein-Volhard. For most of these lines data were directly submitted to the ZFIN database by the ZF-MODELS consortium and they have not yet been sequenced ("unm..." genotypes).

Exelixis, Inc., the Max Planck Institute for Developmental Biology and the ZF-MODELS consortium have kindly permitted us to distribute all of these lines with our standard Material Transfer Agreement, with no further restrictions.

 

Sanger TILLING mutants available

(3-Sep-2013)

We have received the first shipment of sperm samples from the Sanger Mutagenesis Resource, which aims to knock out all protein-coding genes of the zebrafish by chemical mutagenesis and whole-exome sequencing. Starting with library SL4, we will receive sperm samples from all sequenced F1 fish and will take over distribution of the lines from the Sanger Institute, along with the Zebrafish International Resource Center (ZIRC) in Eugene, Oregon.

Please note that we have only two sperm samples per F1, and therefore need to grow up some fish from each requested line to generate more samples. If not enough embryos are generated to send them immediately, we will send you embryos from identified carriers when they are ready. This may increase shipping time to 4 months or more. 

 

New website

(15-Aug-2013)

Internal launch of the new EZRC website.